Glucocorticoids reduce renal NHE8 expression

The proximal tubule reabsorbs most of the filtered bicarbonate which is mediated in large part by Na+/H+ exchange (NHE). We have previously demonstrated that there is an isoform switch during postnatal maturation from NHE8 to NHE3 that is concordant with the postnatal increase in serum glucocorticoi...

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Bibliographic Details
Main Authors: Joseph, Catherine, Gattineni, Jyothsna, Dwarakanath, Vangipuram, Baum, Michel
Format: Online
Language:English
Published: Blackwell Publishing Ltd 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767454/