Burst activity and ultrafast activation kinetics of CaV1.3 Ca2+ channels support presynaptic activity in adult gerbil hair cell ribbon synapses

Auditory information transfer to afferent neurons relies on precise triggering of neurotransmitter release at the inner hair cell (IHC) ribbon synapses by Ca2+ entry through CaV1.3 Ca2+ channels. Despite the crucial role of CaV1.3 Ca2+ channels in governing synaptic vesicle fusion, their elementary...

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Bibliographic Details
Main Authors: Zampini, Valeria, Johnson, Stuart L, Franz, Christoph, Knipper, Marlies, Holley, Matthew C, Magistretti, Jacopo, Masetto, Sergio, Marcotti, Walter
Format: Online
Language:English
Published: Blackwell Science Inc 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3764630/