Specific Extracellular Matrix Remodeling Signature of Colon Hepatic Metastases

To identify genes implicated in metastatic colonization of the liver in colorectal cancer, we collected pairs of primary tumors and hepatic metastases before chemotherapy in 13 patients. We compared mRNA expression in the pairs of patients to identify genes deregulated during metastatic evolution. W...

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Bibliographic Details
Main Authors: Del Rio, Maguy, Mollevi, Caroline, Vezzio-Vie, Nadia, Bibeau, Frédéric, Ychou, Marc, Martineau, Pierre
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3762755/