The Soluble Form of the Cellular Prion Protein Enhances Phagocytic Activity and Cytokine Production by Human Monocytes Via Activation of ERK and NF-κB
The PrPC is expressed in many types of immune cells including monocytes and macrophages, however, its function in immune regulation remains to be elucidated. In the present study, we examined a role for PrPC in regulation of monocyte function. Specifically, the effect of a soluble form of PrPC was s...
| Main Authors: | , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
The Korean Association of Immunologists
2013
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759712/ |