Endogenous progesterone levels and frontotemporal dementia: modulation of TDP-43 and Tau levels in vitro and treatment of the A315T TARDBP mouse model

Endogenous progesterone levels and frontotemporal dementia: modulation of TDP-43 and Tau levels in vitro and treatment of the A315T TARDBP mouse model

Frontotemporal dementia (FTD) is associated with motor neurone disease (FTD-MND), corticobasal syndrome (CBS) and progressive supranuclear palsy syndrome (PSPS). Together, this group of disorders constitutes a major cause of young-onset dementia. One of the three clinical variants of FTD is progress...

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Bibliographic Details
Main Authors: Dang, Theresa N. T., Dobson-Stone, Carol, Glaros, Elias N., Kim, Woojin S., Hallupp, Marianne, Bartley, Lauren, Piguet, Olivier, Hodges, John R., Halliday, Glenda M., Double, Kay L., Schofield, Peter R., Crouch, Peter J., Kwok, John B. J.
Format: Online
Language:English
Published: The Company of Biologists Limited 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759339/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759339/

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