Crosstalk between PKCα and Notch-4 in endocrine-resistant breast cancer cells

Crosstalk between PKCα and Notch-4 in endocrine-resistant breast cancer cells

The Notch pathway is functionally important in breast cancer. Notch-1 has been reported to maintain an estrogen-independent phenotype in estrogen receptor α (ERα)+ breast cancer cells. Notch-4 expression correlates with Ki67. Notch-4 also plays a key role in breast cancer stem-like cells. Estrogen-i...

Full description

Bibliographic Details
Main Authors: Yun, J, Pannuti, A, Espinoza, I, Zhu, H, Hicks, C, Zhu, X, Caskey, M, Rizzo, P, D'Souza, G, Backus, K, Denning, M F, Coon, J, Sun, M, Bresnick, E H, Osipo, C, Wu, J, Strack, P R, Tonetti, D A, Miele, L
Format: Online
Language:English
Published: Nature Publishing Group 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759125/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759125/

Similar Items