Vaccination Directed against the Human Endogenous Retrovirus-K Envelope Protein Inhibits Tumor Growth in a Murine Model System

Human endogenous retrovirus (HERV) genomes are chromosomally integrated in all cells of an individual. They are normally transcriptionally silenced and transmitted only vertically. Enhanced expression of HERV-K accompanied by the emergence of anti-HERV-K-directed immune responses has been observed i...

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Bibliographic Details
Main Authors: Kraus, Benjamin, Fischer, Katrin, Büchner, Sarah M., Wels, Winfried S., Löwer, Roswitha, Sliva, Katja, Schnierle, Barbara S.
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3758348/