Gender-Specific Effects of Genetic Variants within Th1 and Th17 Cell-Mediated Immune Response Genes on the Risk of Developing Rheumatoid Arthritis

The present study was conducted to explore whether single nucleotide polymorphisms (SNPs) in Th1 and Th17 cell-mediated immune response genes differentially influence the risk of rheumatoid arthritis (RA) in women and men. In phase one, 27 functional/tagging polymorphisms in C-type lectins and MCP-1...

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Bibliographic Details
Main Authors: Cáliz, Rafael, Canet, Luz María, Lupiañez, Carmen Belén, Canhão, Helena, Escudero, Alejandro, Filipescu, Ileana, Segura-Catena, Juana, Soto-Pino, María José, Expósito-Ruiz, Manuela, Ferrer, Miguel Ángel, García, Antonio, Romani, Lurdes, González-Utrilla, Alfonso, Vallejo, Teresa, Pérez-Pampin, Eva, Hemminki, Kari, Försti, Asta, Collantes, Eduardo, Fonseca, João Eurico, Sainz, Juan
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3758336/