Enhancement of Transdermal Penetration and Bioavailability of Poorly Soluble Acyclovir Using Solid Lipid Nanoparticles Incorporated in Gel Cream
The objective of this work was to increase the amount of acyclovir in the basal epidermis, site of herpes virus simplex infection, using the solid lipid nanoparticles loaded gel cream as carriers. Solid lipid nanoparticles were prepared by high pressure homogenisation method and incorporated in a se...
Main Authors: | , , |
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Format: | Online |
Language: | English |
Published: |
Medknow Publications & Media Pvt Ltd
2013
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757850/ |