Enhancement of Transdermal Penetration and Bioavailability of Poorly Soluble Acyclovir Using Solid Lipid Nanoparticles Incorporated in Gel Cream

The objective of this work was to increase the amount of acyclovir in the basal epidermis, site of herpes virus simplex infection, using the solid lipid nanoparticles loaded gel cream as carriers. Solid lipid nanoparticles were prepared by high pressure homogenisation method and incorporated in a se...

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Bibliographic Details
Main Authors: Gide, P. S., Gidwani, S. K., Kothule, K. U.
Format: Online
Language:English
Published: Medknow Publications & Media Pvt Ltd 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757850/