Potential therapeutic effects of the simultaneous targeting of the Nrf2 and NF-κB pathways in diabetic neuropathy☆
The Nuclear factor-2 erythroid related factor-2 (Nrf2) is a redox regulated transcription factor involved in the regulation of antioxidant defence systems. It drives the production of endogenous antioxidant defences and detoxifying enzymes. Nuclear factor-kappa light chain enhancer of B cells (NF-κB...
Main Authors: | , , , |
---|---|
Format: | Online |
Language: | English |
Published: |
Elsevier
2013
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757712/ |