Hydrogen peroxide induce modifications of human extracellular superoxide dismutase that results in enzyme inhibition☆

Superoxide dismutase (EC-SOD) controls the level of superoxide in the extracellular space by catalyzing the dismutation of superoxide into hydrogen peroxide and molecular oxygen. In addition, the enzyme reacts with hydrogen peroxide in a peroxidase reaction which is known to disrupt enzymatic activi...

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Bibliographic Details
Main Authors: Gottfredsen, Randi H., Larsen, Ulrike G., Enghild, Jan J., Petersen, Steen V.
Format: Online
Language:English
Published: Elsevier 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757672/