Deletion of microRNA-80 Activates Dietary Restriction to Extend C. elegans Healthspan and Lifespan

Caloric/dietary restriction (CR/DR) can promote longevity and protect against age-associated disease across species. The molecular mechanisms coordinating food intake with health-promoting metabolism are thus of significant medical interest. We report that conserved Caenorhabditis elegans microRNA-8...

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Bibliographic Details
Main Authors: Vora, Mehul, Shah, Mitalie, Ostafi, Silvana, Onken, Brian, Xue, Jian, Ni, Julie Zhouli, Gu, Sam, Driscoll, Monica
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757059/