Biochemical principle of Limulus test for detecting bacterial endotoxins

A hemocyte lysate from horseshoe crab (Limulus) produced a gel, when exposed to Gram-negative bacterial endotoxins, lipopolysaccharides (LPS). This gelation reaction of the lysate, so-called Limulus test, has been widely employed as a simple and very sensitive assay method for endotoxins. Recent bio...

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Bibliographic Details
Main Author: Iwanaga, Sadaaki
Format: Online
Language:English
Published: The Japan Academy 2007
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3756735/