Mutation in the C-Di-AMP Cyclase dacA Affects Fitness and Resistance of Methicillin Resistant Staphylococcus aureus

Faster growing and more virulent strains of methicillin resistant Staphylococcus aureus (MRSA) are increasingly displacing highly resistant MRSA. Elevated fitness in these MRSA is often accompanied by decreased and heterogeneous levels of methicillin resistance; however, the mechanisms for this phen...

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Bibliographic Details
Main Authors: Dengler, Vanina, McCallum, Nadine, Kiefer, Patrick, Christen, Philipp, Patrignani, Andrea, Vorholt, Julia A., Berger-Bächi, Brigitte, Senn, Maria M.
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3754961/