Composite Survival Index to Compare Virulence Changes in Azole-Resistant Aspergillus fumigatus Clinical Isolates

Understanding resistance to antifungal agents in Aspergillus fumigatus is of increasing importance for the treatment of invasive infections in immunocompromised patients. Although a number of molecular resistance mechanisms are described in detail, the potential accompanying virulence changes and im...

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Bibliographic Details
Main Authors: Mavridou, Eleftheria, Meletiadis, Joseph, Jancura, Pavol, Abbas, Saiden, Arendrup, Maiken C., Melchers, Willem J. G., Heskes, Tom, Mouton, Johan W., Verweij, Paul E.
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753310/