Pathogenic Intestinal Bacteria Enhance Prostate Cancer Development via Systemic Activation of Immune Cells in Mice

A role for microbes has been suspected in prostate cancer but difficult to confirm in human patients. We show here that a gastrointestinal (GI) tract bacterial infection is sufficient to enhance prostate intraepithelial neoplasia (PIN) and microinvasive carcinoma in a mouse model. We found that anim...

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Bibliographic Details
Main Authors: Poutahidis, Theofilos, Cappelle, Kelsey, Levkovich, Tatiana, Lee, Chung-Wei, Doulberis, Michael, Ge, Zhongming, Fox, James G., Horwitz, Bruce H., Erdman, Susan E.
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753256/