Increased apical Na+ permeability in cystic fibrosis is supported by a quantitative model of epithelial ion transport
Cystic fibrosis (CF) is caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, which encodes an anion channel. In the human lung CFTR loss causes abnormal ion transport across airway epithelial cells. As a result CF individuals produce thick mucus, suffer persist...
| Main Authors: | , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Blackwell Science Inc
2013
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3752450/ |