Lipofibroadenoma of the thymus: a case report
We observed an unusual case of Lipofibroadenoma (LFA) in the anterior mediastinum with a 21-year-old man, who was detected with a mass on a chest X-ray scan for one month. Thymothymectomy was then performed and the mass was excised completely, in which the tumor was histologically composed of epithe...
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| Format: | Online |
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BioMed Central
2013
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3751155/ |
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pubmed-37511552013-08-24 Lipofibroadenoma of the thymus: a case report Qu, Guimei Yu, Guohua Zhang, Qian Ma, Junjie Wang, Xiaolei Case Report We observed an unusual case of Lipofibroadenoma (LFA) in the anterior mediastinum with a 21-year-old man, who was detected with a mass on a chest X-ray scan for one month. Thymothymectomy was then performed and the mass was excised completely, in which the tumor was histologically composed of epithelial cells, lymphocytes, mature adipose and fibrous tissue. Within the tumor, the fat cells was distributed singly or multifocally under the ground of fibro tissue with hyaline degeneration, and the epithelial cells were arranged as crack structure with lymphocytes infiltrated sparsely. By immunohistochemical staining assay, the epithelial cells were positive for AE1/AE3 and CK19, and the lymphocytes were CD3 and CD20 positive. Based on the histological characters, a diagnosis of LFA was made, and the total follow-up period was determined to be forty six months. The final repeated CT scan revealed no recurring or residual lesions were detected during the post-surgical course. BioMed Central 2013-07-15 /pmc/articles/PMC3751155/ /pubmed/23856156 http://dx.doi.org/10.1186/1746-1596-8-117 Text en Copyright © 2013 Qu et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| repository_type |
Open Access Journal |
| institution_category |
Foreign Institution |
| institution |
US National Center for Biotechnology Information |
| building |
NCBI PubMed |
| collection |
Online Access |
| language |
English |
| format |
Online |
| author |
Qu, Guimei Yu, Guohua Zhang, Qian Ma, Junjie Wang, Xiaolei |
| spellingShingle |
Qu, Guimei Yu, Guohua Zhang, Qian Ma, Junjie Wang, Xiaolei Lipofibroadenoma of the thymus: a case report |
| author_facet |
Qu, Guimei Yu, Guohua Zhang, Qian Ma, Junjie Wang, Xiaolei |
| author_sort |
Qu, Guimei |
| title |
Lipofibroadenoma of the thymus: a case report |
| title_short |
Lipofibroadenoma of the thymus: a case report |
| title_full |
Lipofibroadenoma of the thymus: a case report |
| title_fullStr |
Lipofibroadenoma of the thymus: a case report |
| title_full_unstemmed |
Lipofibroadenoma of the thymus: a case report |
| title_sort |
lipofibroadenoma of the thymus: a case report |
| description |
We observed an unusual case of Lipofibroadenoma (LFA) in the anterior mediastinum with a 21-year-old man, who was detected with a mass on a chest X-ray scan for one month. Thymothymectomy was then performed and the mass was excised completely, in which the tumor was histologically composed of epithelial cells, lymphocytes, mature adipose and fibrous tissue. Within the tumor, the fat cells was distributed singly or multifocally under the ground of fibro tissue with hyaline degeneration, and the epithelial cells were arranged as crack structure with lymphocytes infiltrated sparsely. By immunohistochemical staining assay, the epithelial cells were positive for AE1/AE3 and CK19, and the lymphocytes were CD3 and CD20 positive. Based on the histological characters, a diagnosis of LFA was made, and the total follow-up period was determined to be forty six months. The final repeated CT scan revealed no recurring or residual lesions were detected during the post-surgical course. |
| publisher |
BioMed Central |
| publishDate |
2013 |
| url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3751155/ |
| _version_ |
1612005403845984256 |