Innate B cells: oxymoron or validated concept?

B lymphocytes promote the initial innate interferon response to viral pathogens without the need for antigen receptor activation. B cell dependent IFN production requires the cytokine, lymphotoxin-β. The LTβ pathway is well known to regulate lymphoid organogenesis and homeostasis by differentiating...

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Bibliographic Details
Main Authors: Ware, Carl F, Benedict, Chris
Format: Online
Language:English
Published: F1000Research 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3751138/