MERS-coronavirus replication induces severe in vitro cytopathology and is strongly inhibited by cyclosporin A or interferon-α treatment

Coronavirus (CoV) infections are commonly associated with respiratory and enteric disease in humans and animals. The 2003 outbreak of severe acute respiratory syndrome (SARS) highlighted the potentially lethal consequences of CoV-induced disease in humans. In 2012, a novel CoV (Middle East Respirato...

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Bibliographic Details
Main Authors: de Wilde, Adriaan H., Raj, V. Stalin, Oudshoorn, Diede, Bestebroer, Theo M., van Nieuwkoop, Stefan, Limpens, Ronald W. A. L., Posthuma, Clara C., van der Meer, Yvonne, Bárcena, Montserrat, Haagmans, Bart L., Snijder, Eric J., van den Hoogen, Bernadette G.
Format: Online
Language:English
Published: Society for General Microbiology 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3749523/