Preparation and characterization of monomethoxy poly(ethylene glycol)-poly(ε-caprolactone) micelles for the solubilization and in vivo delivery of luteolin

Luteolin (Lu) is one of the flavonoids with anticancer activity, but its poor water solubility limits its use clinically. In this work, we used monomethoxy poly(ethylene glycol)-poly(e-caprolactone) (MPEG-PCL) micelles to encapsulate Lu by a self-assembly method, creating a water-soluble Lu/MPEG-PCL...

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Bibliographic Details
Main Authors: Qiu, Jin-Feng, Gao, Xiang, Wang, Bi-Lan, Wei, Xia-Wei, Gou, Ma-Ling, Men, Ke, Liu, Xing-Yu, Guo, Gang, Qian, Zhi-Yong, Huang, Mei-Juan
Format: Online
Language:English
Published: Dove Medical Press 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3748903/