Preoperative Localization and Surgical Margins in Conservative Breast Surgery

Breast-conserving surgery (BCS) is the treatment of choice for early breast cancer. The adequacy of surgical margins (SM) is a crucial issue for adjusting the volume of excision and for avoiding local recurrences, although the precise definition of an adequate margins width remains controversial. Mo...

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Main Authors: Corsi, F., Sorrentino, L., Bossi, D., Sartani, A., Foschi, D.
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3748755/
id pubmed-3748755
recordtype oai_dc
spelling pubmed-37487552013-08-28 Preoperative Localization and Surgical Margins in Conservative Breast Surgery Corsi, F. Sorrentino, L. Bossi, D. Sartani, A. Foschi, D. Review Article Breast-conserving surgery (BCS) is the treatment of choice for early breast cancer. The adequacy of surgical margins (SM) is a crucial issue for adjusting the volume of excision and for avoiding local recurrences, although the precise definition of an adequate margins width remains controversial. Moreover, other factors such as the biological behaviour of the tumor and subsequent proper systemic therapies may influence the local recurrence rate (LRR). However, a successful BCS requires preoperative localization techniques or margin assessment techniques. Carbon marking, wire-guided, biopsy clips, radio-guided, ultrasound-guided, frozen section analysis, imprint cytology, and cavity shave margins are commonly used, but from the literature review, no single technique proved to be better among the various ones. Thus, an association of two or more methods could result in a decrease in rates of involved margins. Each institute should adopt its most congenial techniques, based on the senologic equipe experience, skills, and technologies. Hindawi Publishing Corporation 2013 2013-08-05 /pmc/articles/PMC3748755/ /pubmed/23986868 http://dx.doi.org/10.1155/2013/793819 Text en Copyright © 2013 F. Corsi et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Corsi, F.
Sorrentino, L.
Bossi, D.
Sartani, A.
Foschi, D.
spellingShingle Corsi, F.
Sorrentino, L.
Bossi, D.
Sartani, A.
Foschi, D.
Preoperative Localization and Surgical Margins in Conservative Breast Surgery
author_facet Corsi, F.
Sorrentino, L.
Bossi, D.
Sartani, A.
Foschi, D.
author_sort Corsi, F.
title Preoperative Localization and Surgical Margins in Conservative Breast Surgery
title_short Preoperative Localization and Surgical Margins in Conservative Breast Surgery
title_full Preoperative Localization and Surgical Margins in Conservative Breast Surgery
title_fullStr Preoperative Localization and Surgical Margins in Conservative Breast Surgery
title_full_unstemmed Preoperative Localization and Surgical Margins in Conservative Breast Surgery
title_sort preoperative localization and surgical margins in conservative breast surgery
description Breast-conserving surgery (BCS) is the treatment of choice for early breast cancer. The adequacy of surgical margins (SM) is a crucial issue for adjusting the volume of excision and for avoiding local recurrences, although the precise definition of an adequate margins width remains controversial. Moreover, other factors such as the biological behaviour of the tumor and subsequent proper systemic therapies may influence the local recurrence rate (LRR). However, a successful BCS requires preoperative localization techniques or margin assessment techniques. Carbon marking, wire-guided, biopsy clips, radio-guided, ultrasound-guided, frozen section analysis, imprint cytology, and cavity shave margins are commonly used, but from the literature review, no single technique proved to be better among the various ones. Thus, an association of two or more methods could result in a decrease in rates of involved margins. Each institute should adopt its most congenial techniques, based on the senologic equipe experience, skills, and technologies.
publisher Hindawi Publishing Corporation
publishDate 2013
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3748755/
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