Immunoinformatic Docking Approach for the Analysis of KIR3DL1/HLA-B Interaction

KIR3DL1 is among the most interesting receptors studied, within the killer immunoglobulin receptor (KIR) family. Human leukocyte antigen (HLA) class I Bw4 epitope inhibits strongly Natural Killer (NK) cell's activity through interaction with KIR3DL1 receptor, while Bw6 generally does not. This...

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Bibliographic Details
Main Authors: Grifoni, Alba, Montesano, Carla, Patronov, Atanas, Colizzi, Vittorio, Amicosante, Massimo
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747338/