A Large Animal Model for CNGB1 Autosomal Recessive Retinitis Pigmentosa

Retinal dystrophies in dogs are invaluable models of human disease. Progressive retinal atrophy (PRA) is the canine equivalent of retinitis pigmentosa (RP). Similar to RP, PRA is a genetically heterogenous condition. We investigated PRA in the Papillon breed of dog using homozygosity mapping and hap...

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Bibliographic Details
Main Authors: Winkler, Paige A., Ekenstedt, Kari J., Occelli, Laurence M., Frattaroli, Anton V., Bartoe, Joshua T., Venta, Patrick J., Petersen-Jones, Simon M.
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747135/