Genome-Wide Association of Body Fat Distribution in African Ancestry Populations Suggests New Loci

Central obesity, measured by waist circumference (WC) or waist-hip ratio (WHR), is a marker of body fat distribution. Although obesity disproportionately affects minority populations, few studies have conducted genome-wide association study (GWAS) of fat distribution among those of predominantly Afr...

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Main Authors: Liu, Ching-Ti, Monda, Keri L., Taylor, Kira C., Lange, Leslie, Demerath, Ellen W., Palmas, Walter, Wojczynski, Mary K., Ellis, Jaclyn C., Vitolins, Mara Z., Liu, Simin, Papanicolaou, George J., Irvin, Marguerite R., Xue, Luting, Griffin, Paula J., Nalls, Michael A., Adeyemo, Adebowale, Liu, Jiankang, Li, Guo, Ruiz-Narvaez, Edward A., Chen, Wei-Min, Chen, Fang, Henderson, Brian E., Millikan, Robert C., Ambrosone, Christine B., Strom, Sara S., Guo, Xiuqing, Andrews, Jeanette S., Sun, Yan V., Mosley, Thomas H., Yanek, Lisa R., Shriner, Daniel, Haritunians, Talin, Rotter, Jerome I., Speliotes, Elizabeth K., Smith, Megan, Rosenberg, Lynn, Mychaleckyj, Josyf, Nayak, Uma, Spruill, Ida, Garvey, W. Timothy, Pettaway, Curtis, Nyante, Sarah, Bandera, Elisa V., Britton, Angela F., Zonderman, Alan B., Rasmussen-Torvik, Laura J., Chen, Yii-Der Ida, Ding, Jingzhong, Lohman, Kurt, Kritchevsky, Stephen B., Zhao, Wei, Peyser, Patricia A., Kardia, Sharon L. R., Kabagambe, Edmond, Broeckel, Ulrich, Chen, Guanjie, Zhou, Jie, Wassertheil-Smoller, Sylvia, Neuhouser, Marian L., Rampersaud, Evadnie, Psaty, Bruce, Kooperberg, Charles, Manson, JoAnn E., Kuller, Lewis H., Ochs-Balcom, Heather M., Johnson, Karen C., Sucheston, Lara, Ordovas, Jose M., Palmer, Julie R., Haiman, Christopher A., McKnight, Barbara, Howard, Barbara V., Becker, Diane M., Bielak, Lawrence F., Liu, Yongmei, Allison, Matthew A., Grant, Struan F. A., Burke, Gregory L., Patel, Sanjay R., Schreiner, Pamela J., Borecki, Ingrid B., Evans, Michele K., Taylor, Herman, Sale, Michele M., Howard, Virginia, Carlson, Christopher S., Rotimi, Charles N., Cushman, Mary, Harris, Tamara B., Reiner, Alexander P., Cupples, L. Adrienne, North, Kari E., Fox, Caroline S.
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744443/