Biochemical Competition Makes Fatty-Acid β-Oxidation Vulnerable to Substrate Overload

Biochemical Competition Makes Fatty-Acid β-Oxidation Vulnerable to Substrate Overload

Fatty-acid metabolism plays a key role in acquired and inborn metabolic diseases. To obtain insight into the network dynamics of fatty-acid β-oxidation, we constructed a detailed computational model of the pathway and subjected it to a fat overload condition. The model contains reversible and satura...

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Bibliographic Details
Main Authors: van Eunen, Karen, Simons, Sereh M. J., Gerding, Albert, Bleeker, Aycha, den Besten, Gijs, Touw, Catharina M. L., Houten, Sander M., Groen, Bert K., Krab, Klaas, Reijngoud, Dirk-Jan, Bakker, Barbara M.
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744394/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744394/

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