GPCR Heterodimerization in the Reproductive System: Functional Regulation and Implication for Biodiversity

A G protein-coupled receptor (GPCR) functions not only as a monomer or homodimer but also as a heterodimer with another GPCR. GPCR heterodimerization results in the modulation of the molecular functions of the GPCR protomer, including ligand binding affinity, signal transduction, and internalization...

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Bibliographic Details
Main Authors: Satake, Honoo, Matsubara, Shin, Aoyama, Masato, Kawada, Tsuyoshi, Sakai, Tsubasa
Format: Online
Language:English
Published: Frontiers Media S.A. 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744054/