IGF-I, IGF-II, and Insulin Stimulate Different Gene Expression Responses through Binding to the IGF-I Receptor

Insulin and the insulin-like growth factors (IGF)-I and -II are closely related peptides important for regulation of metabolism, growth, differentiation, and development. The IGFs exert their main effects through the IGF-I receptor. Although the insulin receptor is the main physiological receptor fo...

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Bibliographic Details
Main Authors: Versteyhe, Soetkin, Klaproth, Birgit, Borup, Rehannah, Palsgaard, Jane, Jensen, Maja, Gray, Steven G., De Meyts, Pierre
Format: Online
Language:English
Published: Frontiers Media S.A. 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3738877/