Chromosomal deletions and inversions mediated by TALENs and CRISPR/Cas in zebrafish

Chromosomal deletions and inversions mediated by TALENs and CRISPR/Cas in zebrafish

Customized TALENs and Cas9/gRNAs have been used for targeted mutagenesis in zebrafish to induce indels into protein-coding genes. However, indels are usually not sufficient to disrupt the function of non-coding genes, gene clusters or regulatory sequences, whereas large genomic deletions or inversio...

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Bibliographic Details
Main Authors: Xiao, An, Wang, Zhanxiang, Hu, Yingying, Wu, Yingdan, Luo, Zhou, Yang, Zhipeng, Zu, Yao, Li, Wenyuan, Huang, Peng, Tong, Xiangjun, Zhu, Zuoyan, Lin, Shuo, Zhang, Bo
Format: Online
Language:English
Published: Oxford University Press 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737551/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737551/

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