Node of Ranvier disruption as a cause of neurological diseases
Dysfunction and/or disruption of nodes of Ranvier are now recognized as key contributors to the pathophysiology of various neurological diseases. One reason is that the excitable nodal axolemma contains a high density of Nav (voltage-gated Na+ channels) that are required for the rapid and efficient...
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Format: | Online |
Language: | English |
Published: |
American Society for Neurochemistry
2013
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3736360/ |