Node of Ranvier disruption as a cause of neurological diseases

Dysfunction and/or disruption of nodes of Ranvier are now recognized as key contributors to the pathophysiology of various neurological diseases. One reason is that the excitable nodal axolemma contains a high density of Nav (voltage-gated Na+ channels) that are required for the rapid and efficient...

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Bibliographic Details
Main Author: Susuki, Keiichiro
Format: Online
Language:English
Published: American Society for Neurochemistry 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3736360/