MicroRNAs networks in thyroid cancers: focus on miRNAs related to the fascin

miRNAs are non coding ribonucleic acids which are protected with respect to evolution, and have a length of 18–25 nucleotides. microRNAs control the gene expression after transcription, through mRNA destruction or translation processing, and therefore participate in arrangement of the physiologic an...

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Main Authors: Samimi, Hilda, Zaki dizaji, Majid, Ghadami, Mohsen, Shahzadeh fazeli, Abolhasan, Khashayar, Patricia, Soleimani, Masoud, Larijani, Bagher, Haghpanah, Vahid
Format: Online
Language:English
Published: BioMed Central 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3733898/
id pubmed-3733898
recordtype oai_dc
spelling pubmed-37338982013-08-06 MicroRNAs networks in thyroid cancers: focus on miRNAs related to the fascin Samimi, Hilda Zaki dizaji, Majid Ghadami, Mohsen Shahzadeh fazeli, Abolhasan Khashayar, Patricia Soleimani, Masoud Larijani, Bagher Haghpanah, Vahid Review Article miRNAs are non coding ribonucleic acids which are protected with respect to evolution, and have a length of 18–25 nucleotides. microRNAs control the gene expression after transcription, through mRNA destruction or translation processing, and therefore participate in arrangement of the physiologic and pathologic cellular processes; They also may act as oncogene or tumor suppressors. Altered expression of a number of microRNAs is reported in process of progression and metastasis of thyroid cancers. Therefore, identification of these microRNAs may shed a light to oncogenesis pathway of thyroid cancers and their metastasis. In addition, microRNAs might apply as potential biological markers in diagnosis and treatment of thyroid cancers. The changes made in miRNAs profile of thyroid cancers are reviewed in this paper. BioMed Central 2013-07-01 /pmc/articles/PMC3733898/ /pubmed/23815851 http://dx.doi.org/10.1186/2251-6581-12-31 Text en Copyright © 2013 Samimi et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Samimi, Hilda
Zaki dizaji, Majid
Ghadami, Mohsen
Shahzadeh fazeli, Abolhasan
Khashayar, Patricia
Soleimani, Masoud
Larijani, Bagher
Haghpanah, Vahid
spellingShingle Samimi, Hilda
Zaki dizaji, Majid
Ghadami, Mohsen
Shahzadeh fazeli, Abolhasan
Khashayar, Patricia
Soleimani, Masoud
Larijani, Bagher
Haghpanah, Vahid
MicroRNAs networks in thyroid cancers: focus on miRNAs related to the fascin
author_facet Samimi, Hilda
Zaki dizaji, Majid
Ghadami, Mohsen
Shahzadeh fazeli, Abolhasan
Khashayar, Patricia
Soleimani, Masoud
Larijani, Bagher
Haghpanah, Vahid
author_sort Samimi, Hilda
title MicroRNAs networks in thyroid cancers: focus on miRNAs related to the fascin
title_short MicroRNAs networks in thyroid cancers: focus on miRNAs related to the fascin
title_full MicroRNAs networks in thyroid cancers: focus on miRNAs related to the fascin
title_fullStr MicroRNAs networks in thyroid cancers: focus on miRNAs related to the fascin
title_full_unstemmed MicroRNAs networks in thyroid cancers: focus on miRNAs related to the fascin
title_sort micrornas networks in thyroid cancers: focus on mirnas related to the fascin
description miRNAs are non coding ribonucleic acids which are protected with respect to evolution, and have a length of 18–25 nucleotides. microRNAs control the gene expression after transcription, through mRNA destruction or translation processing, and therefore participate in arrangement of the physiologic and pathologic cellular processes; They also may act as oncogene or tumor suppressors. Altered expression of a number of microRNAs is reported in process of progression and metastasis of thyroid cancers. Therefore, identification of these microRNAs may shed a light to oncogenesis pathway of thyroid cancers and their metastasis. In addition, microRNAs might apply as potential biological markers in diagnosis and treatment of thyroid cancers. The changes made in miRNAs profile of thyroid cancers are reviewed in this paper.
publisher BioMed Central
publishDate 2013
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3733898/
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