Topical Rosiglitazone Is an Effective Anti-Scarring Agent in the Cornea

Corneal scarring remains a major cause of blindness world-wide, with limited treatment options, all of which have side-effects. Here, we tested the hypothesis that topical application of Rosiglitazone, a Thiazolidinedione and ligand of peroxisome proliferator activated receptor gamma (PPARγ), can ef...

Full description

Bibliographic Details
Main Authors: Huxlin, Krystel R., Hindman, Holly B., Jeon, Kye-Im, Bühren, Jens, MacRae, Scott, DeMagistris, Margaret, Ciufo, David, Sime, Patricia J., Phipps, Richard P.
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3733781/