miR-29a inhibition normalizes HuR over-expression and aberrant AU-rich mRNA stability in invasive cancer
The activities of RNA-binding proteins are perturbed in several pathological conditions, including cancer. These proteins include tristetraprolin (TTP, ZFP36) and HuR (ELAVL1), which respectively promote the decay or stability of adenylate-uridylate-rich (AU-rich) mRNAs. Here, we demonstrated that i...
Main Authors: | , , , |
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Format: | Online |
Language: | English |
Published: |
John Wiley & Sons, Ltd
2013
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3732382/ |