Effect of the combination of metformin and fenofibrate on glucose homeostasis in diabetic Goto-Kakizaki rats
Metformin has been reported to increase the expression of the glucagon-like peptide-1 (GLP-1) receptor in pancreatic beta cells in a peroxisome proliferator-activated receptor (PPAR)-α-dependent manner. We investigated whether a PPARα agonist, fenofibrate, exhibits an additive or synergistic effect...
Main Authors: | , , , , |
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Format: | Online |
Language: | English |
Published: |
Nature Publishing Group
2013
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731660/ |