Serum TRPM1 Autoantibodies from Melanoma Associated Retinopathy Patients Enter Retinal ON-Bipolar Cells and Attenuate the Electroretinogram in Mice

Serum TRPM1 Autoantibodies from Melanoma Associated Retinopathy Patients Enter Retinal ON-Bipolar Cells and Attenuate the Electroretinogram in Mice

Melanoma-associated retinopathy (MAR) is a paraneoplastic syndrome associated with cutaneous malignant melanoma and the presence of autoantibodies that label neurons in the inner retina. The visual symptoms and electroretinogram (ERG) phenotype characteristic of MAR resemble the congenital visual di...

Full description

Bibliographic Details
Main Authors: Xiong, Wei-Hong, Duvoisin, Robert M., Adamus, Grazyna, Jeffrey, Brett G., Gellman, Celia, Morgans, Catherine W.
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731326/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731326/

Similar Items