Saikosaponin-d, a novel SERCA inhibitor, induces autophagic cell death in apoptosis-defective cells

Autophagy is an important cellular process that controls cells in a normal homeostatic state by recycling nutrients to maintain cellular energy levels for cell survival via the turnover of proteins and damaged organelles. However, persistent activation of autophagy can lead to excessive depletion of...

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Bibliographic Details
Main Authors: Wong, V KW, Li, T, Law, B YK, Ma, E DL, Yip, N C, Michelangeli, F, Law, C KM, Zhang, M M, Lam, K YC, Chan, P L, Liu, L
Format: Online
Language:English
Published: Nature Publishing Group 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3730398/