Impaired surface expression and conductance of the KCNQ4 channel lead to sensorineural hearing loss

Impaired surface expression and conductance of the KCNQ4 channel lead to sensorineural hearing loss

KCNQ4, a voltage-gated potassium channel, plays an important role in maintaining cochlear ion homoeostasis and regulating hair cell membrane potential, both essential for normal auditory function. Mutations in the KCNQ4 gene lead to DFNA2, a subtype of autosomal dominant non-syndromic deafness that...

Full description

Bibliographic Details
Main Authors: Gao, Yanhong, Yechikov, Sergey, Vázquez, Ana E, Chen, Dongyang, Nie, Liping
Format: Online
Language:English
Published: Blackwell Publishing Ltd 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3729637/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3729637/

Similar Items