Induction of TDO2 and IDO2 in Liver by High-Fat Feeding in Mice: Discrepancies with Human Obesity
Low-grade and chronic inflammation is elicited in white adipose tissue in human obesity. The presence of inflammatory molecules leads to an increased tryptophan catabolism through the induction of indoleamine-2,3-dioxygenase-1 (IDO1). In order to characterize the mechanisms underlying this dysregula...
| Main Authors: | , , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Libertas Academica
2013
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3729279/ |