Minor introns are embedded molecular switches regulated by highly unstable U6atac snRNA

Eukaryotes have two types of spliceosomes, comprised of either major (U1, U2, U4, U5, U6) or minor (U11, U12, U4atac, U6atac; <1%) snRNPs. The high conservation of minor introns, typically one amidst many major introns in several hundred genes, despite their poor splicing, has been a long-standin...

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Bibliographic Details
Main Authors: Younis, Ihab, Dittmar, Kimberly, Wang, Wei, Foley, Shawn W, Berg, Michael G, Hu, Karen Y, Wei, Zhi, Wan, Lili, Dreyfuss, Gideon
Format: Online
Language:English
Published: eLife Sciences Publications, Ltd 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3728624/