Wfs1-deficient mice display altered function of serotonergic system and increased behavioral response to antidepressants

It has been shown that mutations in the WFS1 gene make humans more susceptible to mood disorders. Besides that, mood disorders are associated with alterations in the activity of serotonergic and noradrenergic systems. Therefore, in this study, the effects of imipramine, an inhibitor of serotonin (5-...

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Bibliographic Details
Main Authors: Visnapuu, Tanel, Raud, Sirli, Loomets, Maarja, Reimets, Riin, Sütt, Silva, Luuk, Hendrik, Plaas, Mario, Kõks, Sulev, Volke, Vallo, Alttoa, Aet, Harro, Jaanus, Vasar, Eero
Format: Online
Language:English
Published: Frontiers Media S.A. 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3728556/