Sorting of GLUT4 into its insulin-sensitive store requires the Sec1/Munc18 protein mVps45
Insulin stimulates glucose transport by delivering GLUT4 from a specialized storage compartment to the plasma membrane. Subcellular fractionation and an in vitro assay for GLUT4-storage vesicle formation show that the Sec1/Munc18 protein mVps45 is required to correctly sort GLUT4 into this compartme...
| Main Authors: | , , , |
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| Format: | Online |
| Language: | English |
| Published: |
The American Society for Cell Biology
2013
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3727931/ |