A BCL2 promoter polymorphism rs2279115 is not associated with BCL2 protein expression or patient survival in breast cancer patients

The B-cell CLL/lymphoma 2 (BCL2) gene family encodes pro- and anti-apoptotic proteins that are critical regulators of programmed cell death. Higher levels of BCL2 expression in breast tumours have been shown to be an independent prognostic factor for improved survival from breast cancer. The promote...

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Bibliographic Details
Main Authors: Searle, Claire J, Brock, Ian W, Cross, Simon S, Balasubramanian, Sabapathy P, Reed, Malcolm WR, Cox, Angela
Format: Online
Language:English
Published: Springer International Publishing AG 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3725909/