Computational modeling of the p7 monomer from HCV and its interaction with small molecule drugs

Hepatitis C virus p7 protein is a 63 amino acid polytopic protein with two transmembrane domains (TMDs) and one of the prime targets for anti HCV drug development. A bio-inspired modeling pathway is used to generate plausible computational models of the two TMDs forming the monomeric protein model....

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Bibliographic Details
Main Authors: Wang, Yi-Ting, Hsu, Hao-Jen, Fischer, Wolfgang B
Format: Online
Language:English
Published: Springer International Publishing 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3724979/