Association between Ocular Bacterial Carriage and Follicular Trachoma Following Mass Azithromycin Distribution in The Gambia

Trachoma, the world's leading infectious cause of blindness, is caused by ocular infection with the bacterium Chlamydia trachomatis. In low-prevalence settings and following mass treatment campaigns, clinically active follicular trachoma (TF) can be found in the absence of C. trachomatis infect...

Full description

Bibliographic Details
Main Authors:	Burr, Sarah E., Hart, John D., Edwards, Tansy, Baldeh, Ignatius, Bojang, Ebrima, Harding-Esch, Emma M., Holland, Martin J., Lietman, Thomas M., West, Sheila K., Mabey, David C. W., Sillah, Ansumana, Bailey, Robin L.
Format:	Online
Language:	English
Published:	Public Library of Science 2013
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3723595/

id	pubmed-3723595
recordtype	oai_dc
spelling	pubmed-37235952013-08-09 Association between Ocular Bacterial Carriage and Follicular Trachoma Following Mass Azithromycin Distribution in The Gambia Burr, Sarah E. Hart, John D. Edwards, Tansy Baldeh, Ignatius Bojang, Ebrima Harding-Esch, Emma M. Holland, Martin J. Lietman, Thomas M. West, Sheila K. Mabey, David C. W. Sillah, Ansumana Bailey, Robin L. Research Article Trachoma, the world's leading infectious cause of blindness, is caused by ocular infection with the bacterium Chlamydia trachomatis. In low-prevalence settings and following mass treatment campaigns, clinically active follicular trachoma (TF) can be found in the absence of C. trachomatis infection. We carried out this study to investigate associations between ocular carriage of non-chlamydial pathogens and a clinical diagnosis of TF following a mass treatment campaign in The Gambia. We found that children who carried Streptococcus pneumoniae or Haemophilus influenza in their eyes were more likely to have been diagnosed with TF than children who did not carry these pathogens. In The Gambia, non-chlamydial pathogens may be inducing or exacerbating TF in the absence of C. trachomatis infection. Public Library of Science 2013-07-25 /pmc/articles/PMC3723595/ /pubmed/23936573 http://dx.doi.org/10.1371/journal.pntd.0002347 Text en © 2013 Burr et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
repository_type	Open Access Journal
institution_category	Foreign Institution
institution	US National Center for Biotechnology Information
building	NCBI PubMed
collection	Online Access
language	English
format	Online
author	Burr, Sarah E. Hart, John D. Edwards, Tansy Baldeh, Ignatius Bojang, Ebrima Harding-Esch, Emma M. Holland, Martin J. Lietman, Thomas M. West, Sheila K. Mabey, David C. W. Sillah, Ansumana Bailey, Robin L.
spellingShingle	Burr, Sarah E. Hart, John D. Edwards, Tansy Baldeh, Ignatius Bojang, Ebrima Harding-Esch, Emma M. Holland, Martin J. Lietman, Thomas M. West, Sheila K. Mabey, David C. W. Sillah, Ansumana Bailey, Robin L. Association between Ocular Bacterial Carriage and Follicular Trachoma Following Mass Azithromycin Distribution in The Gambia
author_facet	Burr, Sarah E. Hart, John D. Edwards, Tansy Baldeh, Ignatius Bojang, Ebrima Harding-Esch, Emma M. Holland, Martin J. Lietman, Thomas M. West, Sheila K. Mabey, David C. W. Sillah, Ansumana Bailey, Robin L.
author_sort	Burr, Sarah E.
title	Association between Ocular Bacterial Carriage and Follicular Trachoma Following Mass Azithromycin Distribution in The Gambia
title_short	Association between Ocular Bacterial Carriage and Follicular Trachoma Following Mass Azithromycin Distribution in The Gambia
title_full	Association between Ocular Bacterial Carriage and Follicular Trachoma Following Mass Azithromycin Distribution in The Gambia
title_fullStr	Association between Ocular Bacterial Carriage and Follicular Trachoma Following Mass Azithromycin Distribution in The Gambia
title_full_unstemmed	Association between Ocular Bacterial Carriage and Follicular Trachoma Following Mass Azithromycin Distribution in The Gambia
title_sort	association between ocular bacterial carriage and follicular trachoma following mass azithromycin distribution in the gambia
description	Trachoma, the world's leading infectious cause of blindness, is caused by ocular infection with the bacterium Chlamydia trachomatis. In low-prevalence settings and following mass treatment campaigns, clinically active follicular trachoma (TF) can be found in the absence of C. trachomatis infection. We carried out this study to investigate associations between ocular carriage of non-chlamydial pathogens and a clinical diagnosis of TF following a mass treatment campaign in The Gambia. We found that children who carried Streptococcus pneumoniae or Haemophilus influenza in their eyes were more likely to have been diagnosed with TF than children who did not carry these pathogens. In The Gambia, non-chlamydial pathogens may be inducing or exacerbating TF in the absence of C. trachomatis infection.
publisher	Public Library of Science
publishDate	2013
url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3723595/
_version_	1611997983060000768

Association between Ocular Bacterial Carriage and Follicular Trachoma Following Mass Azithromycin Distribution in The Gambia

Similar Items