Mcm10 Self-Association Is Mediated by an N-Terminal Coiled-Coil Domain

Minichromosome maintenance protein 10 (Mcm10) is an essential eukaryotic DNA-binding replication factor thought to serve as a scaffold to coordinate enzymatic activities within the replisome. Mcm10 appears to function as an oligomer rather than in its monomeric form (or rather than as a monomer). Ho...

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Bibliographic Details
Main Authors: Du, Wenyue, Josephrajan, Ajeetha, Adhikary, Suraj, Bowles, Timothy, Bielinsky, Anja-Katrin, Eichman, Brandt F.
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720919/