Identification of small molecules for human hepatocyte expansion and iPS differentiation

Cell-based therapies hold the potential to alleviate the growing burden of liver diseases. Such therapies require human hepatocytes, which, within the stromal context of the liver, are capable of many rounds of replication. However, this ability is lost ex vivo and human hepatocyte sourcing has been...

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Bibliographic Details
Main Authors: Shan, Jing, Schwartz, Robert E., Ross, Nathan T., Logan, David J., Thomas, David, Duncan, Stephen A., North, Trista E., Goessling, Wolfram, Carpenter, Anne E., Bhatia, Sangeeta N.
Format: Online
Language:English
Published: 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720805/