Antimicrobial Activity and Phytochemical Constituents of Leaf Extracts of Cassia auriculata
Plants produce a wide variety of phytochemical constituents, which are secondary metabolites and are used either directly or indirectly in the pharmaceutical industry. ‘For centuries, man has effectively used various components of plants or their extracts for the treatment of many diseases, includin...
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Medknow Publications & Media Pvt Ltd
2013
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3719143/ |
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pubmed-37191432013-07-30 Antimicrobial Activity and Phytochemical Constituents of Leaf Extracts of Cassia auriculata Murugan, T. Wins, J. Albino Murugan, M. Short Communication Plants produce a wide variety of phytochemical constituents, which are secondary metabolites and are used either directly or indirectly in the pharmaceutical industry. ‘For centuries, man has effectively used various components of plants or their extracts for the treatment of many diseases, including bacterial infections. In the present study methanol, chloroform and aqueous extracts of Cassia auriculata leaf were subjected for antimicrobial activity by well-diffusion method against six bacterial strains namely Bacillus cereus, Staphylococcus aureus, Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa and Proteus mirabilis. The results revealed that the methanol and chloroform extracts exhibited strong inhibitory activity against all the tested organisms (zone of inhibition of 12-20 mm), except Pseudomonas aeruginosa (zone of inhibition 10 mm or nil). The aqueous extracts showed moderate activity by ‘Zone of inhibition ≤12 or nil). The extracts were screened for their phytochemical constituents by standard protocols’ and were shown to contain carbohydrates, proteins, alkaloids, flavonoids, steroids, saponins and tannins. The antibacterial activity of these extracts is possibly linked to the presence of flavonoids, steroid, saponins and/or tannins. Further studies are needed to determine the precise active principles from Cassia auriculata. Medknow Publications & Media Pvt Ltd 2013 /pmc/articles/PMC3719143/ /pubmed/23901174 http://dx.doi.org/10.4103/0250-474X.113546 Text en Copyright: © Indian Journal of Pharmaceutical Sciences http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| repository_type |
Open Access Journal |
| institution_category |
Foreign Institution |
| institution |
US National Center for Biotechnology Information |
| building |
NCBI PubMed |
| collection |
Online Access |
| language |
English |
| format |
Online |
| author |
Murugan, T. Wins, J. Albino Murugan, M. |
| spellingShingle |
Murugan, T. Wins, J. Albino Murugan, M. Antimicrobial Activity and Phytochemical Constituents of Leaf Extracts of Cassia auriculata |
| author_facet |
Murugan, T. Wins, J. Albino Murugan, M. |
| author_sort |
Murugan, T. |
| title |
Antimicrobial Activity and Phytochemical Constituents of Leaf Extracts of Cassia auriculata |
| title_short |
Antimicrobial Activity and Phytochemical Constituents of Leaf Extracts of Cassia auriculata |
| title_full |
Antimicrobial Activity and Phytochemical Constituents of Leaf Extracts of Cassia auriculata |
| title_fullStr |
Antimicrobial Activity and Phytochemical Constituents of Leaf Extracts of Cassia auriculata |
| title_full_unstemmed |
Antimicrobial Activity and Phytochemical Constituents of Leaf Extracts of Cassia auriculata |
| title_sort |
antimicrobial activity and phytochemical constituents of leaf extracts of cassia auriculata |
| description |
Plants produce a wide variety of phytochemical constituents, which are secondary metabolites and are used either directly or indirectly in the pharmaceutical industry. ‘For centuries, man has effectively used various components of plants or their extracts for the treatment of many diseases, including bacterial infections. In the present study methanol, chloroform and aqueous extracts of Cassia auriculata leaf were subjected for antimicrobial activity by well-diffusion method against six bacterial strains namely Bacillus cereus, Staphylococcus aureus, Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa and Proteus mirabilis. The results revealed that the methanol and chloroform extracts exhibited strong inhibitory activity against all the tested organisms (zone of inhibition of 12-20 mm), except Pseudomonas aeruginosa (zone of inhibition 10 mm or nil). The aqueous extracts showed moderate activity by ‘Zone of inhibition ≤12 or nil). The extracts were screened for their phytochemical constituents by standard protocols’ and were shown to contain carbohydrates, proteins, alkaloids, flavonoids, steroids, saponins and tannins. The antibacterial activity of these extracts is possibly linked to the presence of flavonoids, steroid, saponins and/or tannins. Further studies are needed to determine the precise active principles from Cassia auriculata. |
| publisher |
Medknow Publications & Media Pvt Ltd |
| publishDate |
2013 |
| url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3719143/ |
| _version_ |
1611996937368633344 |