Modulation of allostery by protein intrinsic disorder

Allostery is an intrinsic property of many globular proteins and enzymes that is indispensable for cellular regulatory and feedback mechanisms. Recent theoretical1 and empirical2 observations indicate that allostery is also manifest in intrinsically disordered proteins (IDPs), which account for a si...

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Bibliographic Details
Main Authors: Ferreon, Allan Chris M., Ferreon, Josephine C., Wright, Peter E., Deniz, Ashok A.
Format: Online
Language:English
Published: 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3718496/