DNA-demethylating and anti-tumor activity of synthetic miR-29b mimics in multiple myeloma

DNA-demethylating and anti-tumor activity of synthetic miR-29b mimics in multiple myeloma

Aberrant DNA methylation plays a relevant role in multiple myeloma (MM) pathogenesis. MicroRNAs (miRNAs) are a class of small non-coding RNAs that recently emerged as master regulator of gene expression by targeting protein-coding mRNAs. However, miRNAs involvement in the regulation of the epigeneti...

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Bibliographic Details
Main Authors: Amodio, Nicola, Leotta, Marzia, Bellizzi, Dina, Di Martino, Maria Teresa, D'Aquila, Patrizia, Lionetti, Marta, Fabiani, Fernanda, Leone, Emanuela, Gullà, Anna Maria, Passarino, Giuseppe, Caraglia, Michele, Negrini, Massimo, Neri, Antonino, Giordano, Antonio, Tagliaferri, Pierosandro, Tassone, Pierfrancesco
Format: Online
Language:English
Published: Impact Journals LLC 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3717964/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3717964/

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