Spliceosome mutations in myelodysplastic syndromes and chronic myelomonocytic leukemia

The recently discovered spliceosome mutations represent a group of acquired genetic alterations that affect both myeloid and lymphoid malignancies. A substantial proportion of patients with myelodysplastic syndromes (MDS), chronic myelomonocytoic leukemia (CMML) or chronic lymphocytic leukemia (CLL)...

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Bibliographic Details
Main Authors: Chesnais, Virginie, Kosmider, Olivier, Damm, Frederik, Itzykson, Raphael, Bernard, Olivier A., Solary, Eric, Fontenay, Michaela
Format: Online
Language:English
Published: Impact Journals LLC 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3717792/